‘Aggressive Keloid’: A Severe Variant of Familial Keloid Scarring
نویسندگان
چکیده
منابع مشابه
Keloid scarring: new treatments ahead.
Keloid disease presents a healthcare challenge: patients suffer from pruritus, pain, inflammation, and cosmetic disfigurement. There is no single effective therapeutic regimen for keloids. Numerous treatment options have been described including occlusive dressings, compression therapy, intralesional steroid injections, laser and radiation therapy, cryosurgery, 5-fluorouracil, interferon, and i...
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BACKGROUND This study is a clinical characterization of keloid scars in an African population comprising three rural tribes with familial keloids. Site distribution, morphologic features, and other characteristics of the scars were studied to assess whether each tribe had a specific scar phenotype. METHODS Keloid scar clinics were set up at Soba Hospital in Khartoum, Sudan, for patient recrui...
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Keloid disease is a fibroproliferative dermal tumor with an unknown etiology that occurs after a skin injury in genetically susceptible individuals. Increased familial aggregation, a higher prevalence in certain races, parallelism in identical twins, and alteration in gene expression all favor a remarkable genetic contribution to keloid pathology. It seems that the environment triggers the dise...
متن کاملNEDD4-1 and PTEN expression in keloid scarring.
Keloid scarring remains a major problem in plastic surgery. The aim of this study was to determine the expression of the PTEN tumor suppressor and NEDD4-1 genes in keloid tissue and explore their effect on the formation of such scarring. Twenty keloid patients were enrolled in the study and underwent surgical removal of keloid tissue. No patient had received chemotherapy and/or radiotherapy pri...
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Purpose: To report the clinical presentation, histopathologic findings, and surgical treatment in a series of cases with primary corneal keloid. Case Reports: Six Iranian patients (a father and two sons, a mother and her daughter, and one isolated male patient) without any history of corneal trauma or systemic diseases were clinically and histologically evaluated for a slowly-growing, white opa...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 2003
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107680309601113